Ankylosing spondylitis is a chronic progressive disease which is common in young and middle-aged men. Lumbosacral pain is common in this disease, which leads to spinal ankylosis and even disability in the late stage and seriously affects the daily work and quality of life of patients. This disease is a key disease in our Department. Inheriting the national famous senior traditional Chinese medicine (TCM) physician Wang Weilan's academic treatment experience, with perfect theoretical guidance, as well as Wang's experienced prescription Qingre Yangyin Chushi pill, Yishen Tongdu mixture, and so on, we determine the clinical treatment and syndrome differentiation based on the patient's condition. In 2011, integrating with traditional exercises such as Taichi and Baduanjin, Mr. Ji Zhongling, the sixth generation descendant of Yang's Taichi, revised Taichi Strenghtening Spine Exercise. Combining with the specific comprehensive therapy of traditional Chinese medicine, a TCM treatment system integrated with internal and external, treatment and rehabilitation has been formed.