Professor Zhou De'an, a member of the third, fourth and fifth batch of veteran Chinese medicine experts of China, is the developer of the academic thought of "Six Acupuncture Therapies", namely treatment of mentality, phlegm, pain, stroke,  tremor, transient tic disorder and hearing loss. Based on the rich experience in acupuncture therapy of regulating mentality, he put forward the view of "regulating mentality before treating disease" and summarized a series of matching treatment methods, which are now widely used in the medical, surgical, gynecological and pediatric treatment of encephalopathy and other diseases related to mental and emotion. Through learning "If a person can stood aloof from worldly fame and success and control his desire, the true qi in his body will work normally and he will not get sick" from Suwen (Plain Questions): Shanggu Tianzhen Lun (On Human Preserving Health Energy in Ancient Times), professor Zhou realized that maintaining the patient's mental stability with acupuncture is an important prerequisite for a good therapeutic effect. Inspired by this, professor Zhou groped out a series of methods of acupuncture for regulating mentality, which was called "Zhou's Acupuncture Therapy of Regulating Mentality".

In this therapy method, he put forward the basic prescription of four acupuncture points for regulating mentality, which expands the application scope of "Shu points of the five zang organs used in combination with Geshu" and "Du Mai 13 Acupuncture Points" founded by Wang Leting, as well as the traditional "Opening Siguan Xue" , thus establishing the acupuncture therapy of regulating mentality by calming, tonifying, tranquilizing and relieving depression. Now, it can be used not only to treat mental and emotional disorders such as stroke, insomnia, depression, anxiety, dementia, attention deficit hyperactivity disorder, transient tic disorder, autism,  emotional disorder, but also can be effectively applied to various diseases closely related to mental and emotion, including pain, climacteric syndrome, Parkinson's disease, hypertension, hearing loss, tinnitus, skin diseases and so on, achieving good therapeutic effect.